Additionally, S371F primarily affecting RBD-directed antibodies was also shown to confer sotrovimab resistance.56 However, these mutations were not found in the BA.2 isolate used in this study (Number 1). BA.2 compared with Delta. Findings Almost no neutralisation of Omicron BA.1 and BA.2 was observed using sera from individuals vaccinated with two doses 6 months earlier, … Continue reading Additionally, S371F primarily affecting RBD-directed antibodies was also shown to confer sotrovimab resistance